SKINFUSION® TECHNOLOGY

Skinfusion® technology is designed to deliver target levels of active ingredients through the skin with optimal adhesion and comfort. The proprietary patch design consists of 5 unique layers and is less than 1 mm thin. All current Agile Therapeutics product candidates utilize Skinfusion technology.

NOVEL PATCH DESIGN KEEPS ACTIVE INGREDIENTS IN PLACE

The innermost layer of a patch with Skinfusion technology contains active ingredients, adhesives, and inactive ingredients that improve delivery of the active ingredients. This is called the Active Matrix.

Two outer layers cover the Active Matrix and contain additional adhesives, but no other active or inactive ingredients. These layers, called the Peripheral Adhesive System, create a ring of adhesive around the edge of the patch. The outer adhesive ring is designed to prevent accumulation of small particles like lint, fibers, dirt, etc.

A barrier layer separates the Active Matrix from the Peripheral Adhesive System, preventing migration of ingredients. The outermost layer of the patch is a soft, flexible fabric designed to provide maximum comfort.